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reacted to SeaWolf-AI's post with ❤️ about 10 hours ago
🔋 Open Materials Challenge, Season 1 — Solid-State Battery Electrolytes A solid-state battery replaces the liquid electrolyte of a lithium-ion cell with a solid. It does not catch fire, it lasts longer, and it can hold more. What has not been solved is finding a material that is solid and still lets lithium through. Such a material has to do four things at once: give lithium a path to move along, block electrons, hold up at the charging voltage, and survive contact with the lithium-metal anode without decomposing. Plenty of materials manage three. Very few manage all four. This challenge looks for candidates, together. You submit one composition — for example Li3YCl6. We score it computationally and place it on the board. There is no prize. Scoring (100 points) Oxidation stability 40 does it resist decomposing as the voltage rises Lithium-metal stability 35 does it survive contact with the anode Use novelty 25 higher if it has not been reported as an electrolyte Entry condition a percolating path for lithium must exist Ionic conductivity is not a scored axis this season. Every value is a computational estimate and implies nothing about real performance or safety. The board also carries seven electrolytes in actual use — LGPS, argyrodite, LLZO, LATP and others. They are scored but hold no rank. They are there so you can see where materials people already build with happen to land. Compositions are private by default. Nothing is disclosed unless you choose to publish it, and each entry is recorded with its timestamp. If a third party asks to discuss a particular entry, we pass the request along — never the submitter's identity, unless they agree to it. Season 1 runs 2026-08-21 to 11-30. A participation guide and a set of prompts are included. 👉 https://huggingface.co/spaces/FINAL-Bench/open-materials-challenge Our sister challenge🧪https://huggingface.co/spaces/FINAL-Bench/open-discovery-challenge
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FINAL-Bench/open-materials-challenge
reacted to SeaWolf-AI's post with 🔥 2 days ago
3,631 candidate molecules arrived in five days, from 83 accounts — roughly 700 a day. Far more than we expected. Thank you. Yesterday we opened the third season and 224 arrived within a day: Chagas disease. Why this disease Around 6 million people live with it, mostly in Latin America (WHO). Many carry it for decades without knowing, while the heart is slowly damaged. There are two drugs and both date from the 1960s, hard enough to tolerate that many patients cannot finish the two-month course. Sixty years without a new drug is not only a scientific problem. Most patients live where development costs cannot be recovered, which is why WHO calls this a neglected tropical disease. But the cost of proposing a candidate and filtering it has changed. So it seemed worth asking whether work nobody funds could be done by many people sharing it out. The problem this season The target is CYP51, the enzyme T. cruzi uses to build its membrane sterols. Block it and the parasite cannot survive. The difficulty is that we carry the same enzyme. Scoring: binding 30 · selectivity 30 · ADMET 15 · whole-cell 10 · novelty 10 · synthesis 5 Selectivity carries 30 points because nobody has solved it. Among the approved azoles on the board as reference compounds, some score 0 on selectivity — not a scorer fault, but the measurement. Taking part Design with any model, submit a SMILES, scored within minutes. Five ready-to-paste prompts per season, and the full rubric is published. Your molecule stays yours; private submission is the default. Prizes — 4,000 USD across three seasons Malaria 30 Sep · 1,000 | Tuberculosis 31 Oct · 2,000 | Chagas 30 Nov · 1,000 We know this does not cover the time you spend. It is a way of saying the work had worth. https://huggingface.co/spaces/FINAL-Bench/open-discovery-challenge
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